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New help for Depression
Brain © Vasiliy Yakobchuk - iStockphotoPeople at risk
A team led by University College London Professors, Michael King and Irwin Nazareth, have developed a test for people at risk from depression. They modelled it on tests for medical conditions such as heart problems, says Professor King, ‘where prediction instruments had been designed over several years.’ The algorithm was tested on 6,000 people between the ages of 16 and 75 who were attending their General Practitioners, not including anyone already suffering from depression. ‘People often think we are medicalising ordinary low mood by making it into a medical condition,’ says Professor King, ‘but in fact, what they don’t realise is that many medical conditions in medicine are the same. There is no way we can measure pain for example, we proceed on the person’s account of it.’
Car Smoke © Maciej korzekwa - iStockphotoMain risk factors
The test measures well-established risk factors for depression such as child abuse, a family history of depression or suicide, personal history of depression, drug and alcohol use, and stresses at home and work. ‘When we pulled them all together,’ says Professor King, ‘we found out that the main risk factors were things like past depression, which is always a strong risk factor, family history, experiences of discrimination such as age, or race, or sexual orientation.’  There was quite a lot around people having difficulties at work and feeling unsupported.
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Media interest
When the team released the findings they put it up on a website with the test, but they didn’t expect such media publicity and interest. ‘We’ve had over 50,000 people visiting,’ says Professor King. The website was intended for academics interested in the research but struck a chord among the general public. They are assessing whether to restrict access to the website. They are concerned that people taking the test might be upset or fearful of their future. This is something they are addressing in the next steps of the research.

‘We are trying to develop an application,’ says Professor King, ‘to go out and ask patients, their relatives, their doctors and nurses in General Practice, ‘What shall we do about this?’ If someone comes up with a high score, what is the best kind of intervention? Will they be made anxious by knowing their risk?’ The aim is to develop the tool so that doctors can help prevent major depression.

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