Infectious diseases and diabetes are two of the leading causes of morbidity in Bangladesh. A partnership under the INSPIRE programme of The British Council, between The University of Dhaka, The University of Nottingham and The University of Dundee will conduct investigative research that may have significant impact in combating both of these public health concerns. The two –pronged research will be conducted by 13 researchers from the three universities. The first team will focus on the misuse of antibiotics.
Antibiotics are our foremost weapon against the onslaught of infectious diseases. However, indiscriminate usage of antibiotics has severe repercussions. When antibiotics are overused, certain microbes develop resistance to them and evolve into new strains of pathogen who no longer respond to these drugs. This phenomenon is known as drug resistance. The rise of drug resistant pathogen has increased human mortality, suffering and healthcare expenditures all across the globe.
Existing data shows that around 25 to 75 per cent of all the prescriptions issued in Bangladesh indicate misuse of antibiotics. This poses a serious threat of massive outbreak of multidrug resistant pathogens.
The partnership is focusing on understanding the extent of the misuse of antibiotics and the prevalence of drug resistance pathogens in Bangladesh. Seven researches from The University of Dhaka and The University of Nottingham will conduct their research on 12 government hospitals from six districts. They will also focus on finding out the causes behind such indulgent prescribing behaviour of the doctors and design proper interventions and awareness programs that will promote a rational employment of antibiotics.
The second team will focus on the rise of Type 2 Diabetes Mellitus in Bangladesh.
Research suggests that Type 2 Diabetes Mellitus may be caused by the polymorphism of certain genes. This polymorphism also affects the efficacy of the drugs used for diabetic management. There is a lack of information on polymorphism of these genes among the Bengali populace and this data is necessary for a proper understanding of the rise of diabetes in Bangladesh.
The researchers will isolate the genes from the DNAs of 125 subjects and study their polymorphism. They will also test diabetic drug efficacy on the Bengali population through recombinant gene technology. This study has the potential of breaking new grounds in the management of the disease and reduction of adverse drugs reactions.
Links : www.dundee.ac.uk/biomedres
For further information contact : Omar.Faruque@bd.britishcouncil.org